2018年

  • Shono Y, Sugimori H, Matsuo R, Fukushima Y, Wakisaka Y, Kuroda J, Ago T, Kamouchi M, Kitazono T

    Safety of Antithrombotic Therapy for Patients With Acute Ischemic Stroke Harboring Unruptured Intracranial Aneurysm.

    Int J Stroke 13(7): 734-742 pubmed

  • Kiyuna F, Sato N, Matsuo R, Kamouchi M, Hata J, Wakisaka Y, Kuroda J, Ago T, Kitazono T

    Association of Embolic Sources With Cause-Specific Functional Outcomes Among Adults With Cryptogenic Stroke.

    JAMA Netw Open 1(5): e182953 pubmed

  • Ago T, Matsuo R, Hata J, Wakisaka Y, Kuroda J, Kitazono T, Kamouchi M, Fukuoka Stroke Registry Investigators

    Insulin resistance and clinical outcomes after acute ischemic stroke.

    Neurology 90(17): e1470-e1477 pubmed

  • Komorita Y, Iwase M, Fujii H, Ohkuma T, Ide H, Jodai-Kitamura T, Sumi A, Yoshinari M, Nakamura U, Kang D, Kitazono T

    Impact of Body Weight Loss From Maximum Weight on Fragility Bone Fractures in Japanese Patients With Type 2 Diabetes: The Fukuoka Diabetes Registry.

    Diabetes Care 41(5): 1061-7 pubmed

  • Iwase M, Fujii H, Nakamura U, Ohkuma T, Ide H, Jodai-Kitamura T, Sumi A, Komorita Y, Yoshinari M, Kitazono T

    Incidence of diabetic foot ulcer in Japanese patients with type 2 diabetes mellitus: The Fukuoka diabetes registry.

    Diabetes Res Clin Pract 137: 183-9 pubmed

  • Komorita Y, Iwase M, Fujii H, Ide H, Ohkuma T, Jodai-Kitamura T, Sumi A, Yoshinari M, Nakamura U, Kitazono T

    The serum creatinine to cystatin C ratio predicts bone fracture in patients with type 2 diabetes: The Fukuoka Diabetes Registry.

    Diabetes Res Clin Pract 146: 202-10 pubmed

  • Sumi A, Iwase M, Nakamura U, Fujii H, Ohkuma T, Ide H, Jodai-Kitamura T, Komorita Y, Yoshinari M, Kitazono T

    Impact of age at menarche on obesity and glycemic control in Japanese patients with type 2 diabetes: Fukuoka Diabetes Registry.

    J Diabetes Investig 9(5): 1216-23 pubmed

  • Tanaka S, Ninomiya T, Katafuchi R, Masutani K, Tsuchimoto A, Tokumoto M, Hirakata H, Hiroaki Ooboshi, Kitazono T, Tsuruya K

    Secular trends in the incidence of end-stage renal disease and its risk factors in Japanese patients with immunoglobulin A nephropathy.

    Nephrol Dial Transplant 33(6): 963-71 pubmed

  • Kawai Y, Masutani K, Torisu K, Katafuchi R, Tanaka S, Tsuchimoto A, Mitsuki K, Tsuruya K, Kitazono T

    Association between serum albumin level and incidence of end-stage renal disease in patients with Immunoglobulin A nephropathy: A possible role of albumin as an antioxidant agent.

    PLoS One 13(5): e0196655 pubmed

  • Furue M, Hashimoto-Hachiya A, Tsuji G

    Antioxidative Phytochemicals Accelerate Epidermal Terminal Differentiation via the AHR-OVOL1 Pathway: Implications for Atopic Dermatitis.

    Acta Derm Venereol 98(10): 918-923 pubmed

  • Furue M, Fuyuno Y, Mitoma C, Uchi H, Tsuji G

    Therapeutic Agents with AHR Inhibiting and NRF2 Activating Activity for Managing Chloracne.

    Antioxidants (Basel) 7(7): 90 pubmed

  • Akahane M, Matsumoto S, Kanagawa Y, Mitoma C, Uchi H, Yoshimura T, Furue M, Imamura T

    Long-Term Health Effects of PCBs and Related Compounds: A Comparative Analysis of Patients Suffering from Yusho and the General Population.

    Arch Environ Contam Toxicol 74(2): 203-217 pubmed

  • Hirakawa S, Miyawaki T, Hori T, Kajiwara J, Katsuki S, Hirano M, Yoshinouchi Y, Iwata H, Mitoma C, Furue M

    Accumulation properties of polychlorinated biphenyl congeners in Yusho patients and prediction of their cytochrome P450-dependent metabolism by in silico analysis.

    Environ Sci Pollut Res Int 25(17): 16455-16463 pubmed

  • Miyawaki T, Sugihara M, Hirakawa S, Hori T, Kajiwara J, Katsuki S, Mitoma C, Furue M

    Compound-specific isotopic and congener-specific analyses of polychlorinated biphenyl in the heat medium and rice oil of the Yusho incident.

    Environ Sci Pollut Res Int 25(17): 16464-16471 pubmed

  • Takemura M, Nakahara T, Hashimoto-Hachiya A, Furue M, Tsuji G

    Glyteer, Soybean Tar, Impairs IL-4/Stat6 Signaling in Murine Bone Marrow-Derived Dendritic Cells: The Basis of Its Therapeutic Effect on Atopic Dermatitis.

    Int J Mol Sci 19(4): 1169 pubmed

  • Hashimoto-Hachiya A, Tsuji G, Murai M, Yan X, Furue M

    Upregulation of FLG, LOR, and IVL Expression by Rhodiola crenulata Root Extract via Aryl Hydrocarbon Receptor: Differential Involvement of OVOL1.

    Int J Mol Sci 19(6): 1654 pubmed

  • Murai M, Tsuji G, Hashimoto-Hachiya A, Kawakami Y, Furue M, Mitoma C

    An endogenous tryptophan photo-product, FICZ, is potentially involved in photo- aging by reducing TGF-β-regulated collagen homeostasis.

    J Dermatol Sci 89(1): 19-26 pubmed

  • Tsuji G, Ito T, Chiba T, Mitoma C, Nakahara T, Uchi H, Furue M

    The role of the OVOL1-OVOL2 axis in normal and diseased human skin.

    J Dermatol Sci 90(3): 227-231 pubmed

  • Kiyomatsu-Oda M, Uchi H, Morino-Koga S, Furue M

    Protective role of 6-formylindolo[3,2-b]carbazole (FICZ), an endogenous ligand for arylhydrocarbon receptor, in chronic mite-induced dermatitis.

    J Dermatol Sci 90(3): 284-294 pubmed

  • Murai M, Yamamura K, Hashimoto-Hachiya A, Tsuji G, Furue M, Mitoma C

    Tryptophan photo-product FICZ upregulates AHR/MEK/ERK-mediated MMP1 expression: Implications in anti-fibrotic phototherapy.

    J Dermatol Sci 91(1): 97-103 pubmed

  • Mitamura Y, Murai M, Mitoma C, Furue M

    NRF2 Activation Inhibits Both TGF-β1- and IL-13-Mediated Periostin Expression in Fibroblasts: Benefit of Cinnamaldehyde for Antifibrotic Treatment.

    Oxid Med Cell Longev 2018: 2475047 pubmed

  • Tanaka Y, Uchi H, Hashimoto-Hachiya A, Furue M

    Tryptophan Photoproduct FICZ Upregulates IL1A, IL1B, and IL6 Expression via Oxidative Stress in Keratinocytes.

    Oxid Med Cell Longev 2018: 9298052 pubmed

  • Fuyuno Y, Uchi H, Yasumatsu M, Morino-Koga S, Tanaka Y, Mitoma C, Furue M

    Perillaldehyde Inhibits AHR Signaling and Activates NRF2 Antioxidant Pathway in Human Keratinocytes.

    Oxid Med Cell Longev 2018: 9524657 pubmed

  • Furuta Y, Hata J, Mukai N, Hirakawa Y, Ago T, Kitazono T, Kiyohara Y, Ninomiya T

    Secular trends in the incidence, risk factors, and prognosis of transient ischemic attack in Japan: the Hisayama Study.

    Atherosclerosis 273: 84-90 pubmed

  • Ohkuma T, Ninomiya T, Tomiyama H, Kario K, Hoshide S, Kita Y, Inoguchi T, Maeda Y, Kohara K, Tabara Y, Nakamura M, Ohkubo T, Watada H, Munakata M, Ohishi M, Ito N, Nakamura M, Shoji T, Vlachopoulos C, Aboyans V, Yamashina A, collaborative group for the Japan Brachial-Ankle pulse wave VELocity individual participant data meta-analysis of prospective studies to examine the significance of the Ankle-Brachial Index (J-BAVEL-ABI)

    Ankle-brachial index measured by oscillometry is predictive for cardiovascular disease and premature death in the Japanese population: an individual participant data meta-analysis.

    Atherosclerosis 275: 141-148 pubmed

  • Honda T, Yoshida D, Hata J, Hirakawa Y, Ishida Y, Shibata M, Sakata S, Kitazono T, Ninomiya T

    Development and validation of modified risk prediction models for cardiovascular disease and its subtypes: the Hisayama Study.

    Atherosclerosis 279: 38-44 pubmed

  • Peters SAE, Wang X, Lam TH, Kim HC, Ho S, Ninomiya T, Knuiman M, Vaartjes I, Bots ML, Woodward M, Asia Pacific Cohort Studies Collaboration (Ninomiya T, Hata J, Hirakawa Y)

    Clustering of risk factors and the risk of incident cardiovascular disease in Asian and Caucasian populations: results from the Asia Pacific Cohort Studies Collaboration.

    BMJ Open 8(3): e019335 pubmed

  • Okabayashi Y, Tsuboi N, Amano H, Miyazaki Y, Kawamura T, Ogura M, Narita I, Ninomiya T, Yokoyama H, Yokoo T

    Distribution of nephrologists and regional variation in the clinical severity of IgA nephropathy at biopsy diagnosis in Japan: a cross-sectional study.

    BMJ Open 8(10): e024317 pubmed

  • Shijo M, Honda H, Suzuki SO, Hamasaki H, Hokama M, Abolhassani N, Nakabeppu Y, Ninomiya T, Kitazono T, Iwaki T

    Association of adipocyte enhancer-binding protein 1 with Alzheimer's disease pathology in human hippocampi.

    Brain Pathol 28(1): 58-71 pubmed

  • Lo C, Toyama T, Wang Y, Lin J, Hirakawa Y, Jun M, Cass A, Hawley CM, Pilmore H, Badve SV, Perkovic V, Zoungas S

    Insulin and glucose-lowering agents for treating people with diabetes and chronic kidney disease.

    Cochrane Database Syst Rev 9(9): CD011798 pubmed

  • Tanaka M, Honda T, Yamakage H, Hata J, Yoshida D, Hirakawa Y, Shibata M, Inoue T, Kusakabe T, Satoh-Asahara N, Ninomiya T

    A potential novel pathological implication of serum soluble triggering receptor expressed on myeloid cell 2 in insulin resistance in a general Japanese population: the Hisayama Study.

    Diabetes Res Clin Pract 146: 225-232 pubmed

  • Iida M, Ikeda F, Hata J, Hirakawa Y, Ohara T, Mukai N, Yoshida D, Yonemoto K, Esaki M, Kitazono T, Kiyohara Y, Ninomiya T

    Development and validation of a risk assessment tool for gastric cancer in a general Japanese population.

    Gastric Cancer 21(3): 383-390 pubmed

  • Yamaguchi-Kabata Y, Morihara T, Ohara T, Ninomiya T, Takahashi A, Akatsu H, Hashizume Y, Hayashi N, Shigemizu D, Boroevich KA, Ikeda M, Kubo M, Takeda M, Tsunoda T

    Integrated analysis of human genetic association study and mouse transcriptome suggests LBH and SHF genes as novel susceptible genes for amyloid-β accumulation in Alzheimer's disease.

    Hum Genet 137(6-7): 521-533 pubmed

  • Tomiyama H, Ohkuma T, Ninomiya T, Mastumoto C, Kario K, Hoshide S, Kita Y, Inoguchi T, Maeda Y, Kohara K, Tabara Y, Nakamura M, Ohkubo T, Watada H, Munakata M, Ohishi M, Ito N, Nakamura M, Shoji T, Vlachopoulos C, Yamashina A, collaborative group for J-BAVEL-IAD

    Simultaneously measured interarm blood pressure difference and stroke: an individual participants data meta-analysis.

    Hypertension 71(6): 1030-1038 pubmed

  • NCD Risk Factor Collaboration (NCD-RisC)(Ninomiya T, Hata J)

    Contributions of mean and shape of blood pressure distribution to worldwide trends and variations in raised blood pressure: a pooled analysis of 1018 population-based measurement studies with 88.6 million participants.

    Int J Epidemiol 47(3): 872-883i pubmed

  • Shibata M, Ohara T, Yoshida D, Hata J, Mukai N, Kawano H, Kanba S, Kitazono T, Ninomiya T

    Association between the ratio of serum arachidonic acid to eicosapentaenoic acid and the presence of depressive symptoms in a general Japanese population: the Hisayama Study.

    J Affect Disord 237: 73-79 pubmed

  • Ohara T, Honda T, Hata J, Yoshida D, Mukai N, Hirakawa Y, Shibata M, Kishimoto H, Kitazono T, Kanba S, Ninomiya T

    Association between daily sleep duration and risk of dementia and mortality in a Japanese community.

    J Am Geriatr Soc 66(10): 1911-1918 pubmed

  • Takae K, Hata J, Ohara T, Yoshida D, Shibata M, Mukai N, Hirakawa Y, Kishimoto H, Tsuruya K, Kitazono T, Kiyohara Y, Ninomiya T

    Albuminuria increases the risks for both alzheimer disease and vascular dementia in community-dwelling Japanese elderly: the Hisayama Study.

    J Am Heart Assoc 7(2): e006693 pubmed

  • Hirata A, Sugiyama D, Watanabe M, Tamakoshi A, Iso H, Kotani K, Kiyama M, Yamada M, Ishikawa S, Murakami Y, Miura K, Ueshima H, Okamura T, Evidence for Cardiovascular Prevention from Observational Cohorts in Japan (EPOCH-JAPAN) Research Group (Ninomiya T, Kiyohara Y)

    Association of extremely high levels of high-density lipoprotein cholesterol with cardiovascular mortality in a pooled analysis of 9 cohort studies including 43,407 individuals: The EPOCH-JAPAN study.

    J Clin Lipidol 12(3): 674-684 pubmed

  • Chen T, Kishimoto H, Honda T, Hata J, Yoshida D, Mukai N, Shibata M, Ninomiya T, Kumagai S

    Patterns and levels of sedentary behavior and physical activity in a general Japanese population: the Hisayama Study.

    J Epidemiol 28(5): 260-265 pubmed

  • Nagahata T, Nakamura M, Ojima T, Kondo I, Ninomiya T, Yoshita K, Arai Y, Ohkubo T, Murakami K, Nishi N, Murakami Y, Takashima N, Okuda N, Kadota A, Miyagawa N, Kondo K, Okamura T, Ueshima H, Okayama A, Miura K

    Relationships among food group intakes, household expenditure, and education attainment in a general Japanese population: NIPPON DATA2010.

    J Epidemiol 28 Suppl 3(Suppl 3): S23-S28 pubmed

  • Murakami K, Ohkubo T, Nakamura M, Ninomiya T, Ojima T, Shirai K, Nagahata T, Kadota A, Okuda N, Nishi N, Okamura T, Ueshima H, Okayama A, Miura K

    Socioeconomic inequalities in oral health among middle-aged and elderly Japanese: NIPPON DATA2010.

    J Epidemiol 28 Suppl 3(Suppl 3): S59-S65 pubmed

  • Asakawa M, Takeshita T, Furuta M, Kageyama S, Takeuchi K, Hata J, Ninomiya T, Yamashita Y

    Tongue microbiota and oral health status in community-dwelling elderly adults.

    mSphere 3(4): e00332-18 pubmed

  • MEGASTROKE Consortium (Ninomiya T, Hata J)

    GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomes.

    Nat Commun 9(1): 5141 pubmed

  • MEGASTROKE Consortium( Ninomiya T, Hata J)

    Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes.

    Nat Genet 50(4): 524-537 pubmed

  • Tanaka S, Ninomiya T, Katafuchi R, Masutani K, Tsuchimoto A, Tokumoto M, Hirakata H, Ooboshi H, Kitazono T, Tsuruya K

    Secular trends in the incidence of end-stage renal disease and its risk factors in Japanese patients with immunoglobulin A nephropathy.

    Nephrol Dial Transplant 33(6): 963-971 pubmed

  • Yubi T, Hata J, Ohara T, Mukai N, Hirakawa Y, Yoshida D, Gotoh S, Hirabayashi N, Furuta Y, Ago T, Kitazono T, Kiyohara Y, Ninomiya T

    Prevalence of and risk factors for cerebral microbleeds in a general Japanese elderly community.

    Neurol Clin Pract 8(3): 223-231 pubmed

  • Ago T, Matsuo R, Hata J, Wakisaka Y, Kuroda J, Kitazono T, Kamouchi M, Fukuoka Stroke Registry Investigators

    Insulin resistance and clinical outcomes after acute ischemic stroke.

    Neurology 90(17): e1470-e1477 pubmed

  • Oshima M, Toyama T, Haneda M, Furuichi K, Babazono T, Yokoyama H, Iseki K, Araki S, Ninomiya T, Hara S, Suzuki Y, Iwano M, Kusano E, Moriya T, Satoh H, Nakamura H, Shimizu M, Hara A, Makino H, Wada T, Research Group of Diabetic Nephropathy, Ministry of Health, Labour, and Welfare of Japan

    Estimated glomerular filtration rate 12line and risk of end-stage renal disease in type 2 diabetes.

    PLoS One 13(8): e0201535 pubmed

  • Takeuchi K, Matsumoto K, Furuta M, Fukuyama S, Takeshita T, Ogata H, Suma S, Shibata Y, Shimazaki Y, Hata J, Ninomiya T, Nakanishi Y, Inoue H, Yamashita Y

    Periodontal status and lung function 12line in the community: the Hisayama Study.

    Sci Rep 8(1): 13354 pubmed

  • Fujiwara K, Yasuda M, Hata J, Oshima Y, Hashimoto S, Yoshitomi T, Kiyohara Y, Ishibashi T, Ninomiya T, Sonoda KH

    Prevalence and risk factors for polypoidal choroidal vasculopathy in a general Japanese population: the Hisayama Study.

    Semin Ophthalmol 33(6): 813-819 pubmed

  • VARIABLE BRAIN consortium (Ninomiya T, Ohara T, Oishi E)

    The association between blood pressure variability (BPV) with dementia and cognitive function: a systematic review and meta-analysis protocol.

    Syst Rev 7(1): 163 pubmed

© 2020- Center for Cohort Studies, Graduate School of Medical Sciences, Kyushu University.