九州大学 大学院 医学研究院

Kurogi A, Nishimura A, Nishimura K, Kada A, Onozuka D, Hagihara A, Ogasawara K, Shiokawa Y, Kitazono T, Arimura K, Iihara K; J-ASPECT Study Collaborators.

Temporal trends and geographical disparities in comprehensive stroke centre capabilities in Japan from 2010 to 2018.

BMJ Open 10(8): e033055

Komorita Y, Iwase M, Fujii H, Ohkuma T, Ide H, Jodai-Kitamura T, Yoshinari M, Oku Y, Higashi T, Nakamura U, Kitazono T

Additive effects of green tea and coffee on all-cause mortality in patients with type 2 diabetes mellitus: the Fukuoka Diabetes Registry.

BMJ Open Diabetes Res Care 8(1): e001252

Kitagawa K, Toyoda K, Kitazono T, Nishikawa M, Nanto S, Ikeda Y, Abe K, Ogawa A

Safety and Efficacy of Prasugrel in Elderly/Low Body Weight Japanese Patients with Ischemic Stroke: Randomized PRASTRO-II.

Cerebrovasc Dis 49(2): 152-159

Sato N, Matsuo R, Kiyuna F, Nakamura K, Hata J, Wakisaka Y, Ago T, Kamouchi M, Kitazono T; collab on behalf of the Fukuoka Stroke Registry Investigators.

Anticoagulation and Risk of Stroke Recurrence in Patients with Embolic Stroke of Undetermined Source Having No Potential Source of Embolism.

Cerebrovasc Dis 49(6): 601-608

Arase H, Yamada S, Tanaka S, Tokumoto M, Tsuruya K, Nakano T, Kitazono T

Association Between Plasma Intact Parathyroid Hormone Levels and the Prevalence of Atrial Fibrillation in Patients With Chronic Kidney Disease -The Fukuoka Kidney Disease Registry Study.

Circ J 84(7): 1105-1111

Komorita Y, Iwase M, Fujii H, Ohkuma T, Ide H, Yoshinari M, Oku Y, Nakamura U, Kitazono T

Both hypo- and hyperglycaemia are associated with increased fracture risk in Japanese people with type 2 diabetes: the Fukuoka Diabetes Registry.

Diabet Med 37(5): 838-847

Shibahara T, Ago T, Nakamura K, Tachibana M, Yoshikawa Y, Komori M, Yamanaka K, Wakisaka Y, Kitazono T

Pericyte-Mediated Tissue Repair through PDGFRβ Promotes Peri-Infarct Astrogliosis, Oligodendrogenesis, and Functional Recovery after Acute Ischemic Stroke.

eNeuro 7(2): ENEURO.0474-19.2020.

Komorita Y, Iwase M, Idewaki Y, Fujii H, Ohkuma T, Ide H, Jodai-Kitamura T, Yoshinari M, Murao-Kimura A, Oku Y, Nakamura U, Kitazono T

Impact of hip fracture on all-cause mortality in Japanese patients with type 2 diabetes mellitus: The Fukuoka Diabetes Registry.

J Diabetes Investig 11(1): 62-69

Iwase M, Komorita Y, Fujii H, Ohkuma T, Ide H, Yoshinari M, Oku Y, Higashi T, Nakamura U, Kitazono T

Incidence of severe hypoglycemia and its association with serum adiponectin in Japanese patients with type 1 and insulin-treated type 2 diabetes: the Fukuoka Diabetes Registry.

J Diabetes Investig 11(5): 1258-1264

Kurogi R, Kada A, Ogasawara K, Kitazono T, Sakai N, Hashimoto Y, Shiokawa Y, Miyachi S, Matsumaru Y, Iwama T, Tominaga T, Onozuka D, Nishimura A, Arimura K, Kurogi A, Ren N, Hagihara A, Nakaoku Y, Arai H, Miyamoto S, Nishimura K, Iihara K

Effects of case volume and comprehensive stroke center capabilities on patient outcomes of clipping and coiling for subarachnoid hemorrhage.

J Neurosurg 134: 929-939

Matsumoto K, Nohara Y, Wakata Y, Yamashita T, Kozuma Y, Sugeta R, Yamakawa M, Yamauchi F, Miyashita E, Takezaki T, Yamashiro S, Nishi T, Machida J, Soejima H, Kamouchi M, Nakashima N.

Impact of a learning health system on acute care and medical complications after intracerebral hemorrhage.

Learn Health Syst 5(2): e10223

Ido K, Kurogi R, Kurogi A, Nishimura K, Arimura K, Nishimura A, Ren N, Kada A, Matsuo R, Onozuka D, Hagihara A, Takagishi S, Yamagami K, Takegami M, Nohara Y, Nakashima N, Kamouchi M, Date I, Kitazono T, Iihara K; J-ASPECT Study Collaborators

Effect of treatment modality and cerebral vasospasm agent on patient outcomes after aneurysmal subarachnoid hemorrhage in the elderly aged 75 years and older.

PLoS One 14(4): e0230953

Shibahara T, Ago T, Tachibana M, Nakamura K, Yamanaka K, Kuroda J, Wakisaka Y, Kitazono T

Reciprocal Interaction Between Pericytes and Macrophage in Poststroke Tissue Repair and Functional Recovery.

Stroke 50(10): 3095-3106

Matsuo R, Ago T, Kiyuna F, Sato N, Nakamura K, Kuroda J, Wakisaka Y, Kitazono T; Fukuoka Stroke Registry Investigators.

Smoking Status and Functional Outcomes After Acute Ischemic Stroke.

Stroke 51(3): 846-852

Mizoguchi T, Tanaka K, Toyoda K, Yoshimura S, Itabashi R, Takagi M, Todo K, Shiozawa M, Yagita Y, Yoshimoto T, Terasaki T, Yamagami H, Takizawa S, Inoue M, Kamiyama K, Ihara M, Okada Y, Kitazono T, Koga M; SAMURAI Study Investigators

Early Initiation of Direct Oral Anticoagulants After Onset of Stroke and Short-and Long-Term Outcomes of Patients With Nonvalvular Atrial Fibrillation.

Stroke 51(3): 883-891

Matsumoto K, Nohara Y, Soejima H, Yonehara T, Nakashima N, Kamouchi M

Stroke Prognostic Scores and Data-Driven Prediction of Clinical Outcomes After Acute Ischemic Stroke.

Stroke 51(5): 1477-1483

Koga M, Yamamoto H, Inoue M, Asakura K, Aoki J, Hamasaki T, Kanzawa T, Kondo R, Ohtaki M, Itabashi R, Kamiyama K, Iwama T, Nakase T, Yakushiji Y, Igarashi S, Nagakane Y, Takizawa S, Okada Y, Doijiri R, Tsujino A, Ito Y, Ohnishi H, Inoue T, Takagi Y, Hasegawa Y, Shiokawa Y, Sakai N, Osaki M, Uesaka Y, Yoshimura S, Urabe T, Ueda T, Ihara M, Kitazono T, Sasaki M, Oita A, Yoshimura S, Fukuda-Doi M, Miwa K, Kimura K, Minematsu K, Toyoda K; THAWS Trial Investigators

Thrombolysis With Alteplase at 0.6 mg/kg for Stroke With Unknown Time of Onset: A Randomized Controlled Trial.

Stroke 51(5): 1530-1538

Tsuchimoto A, Matsukuma Y, Ueki K, Tanaka S, Masutani K, Nakagawa K, Mitsuki K, Uesugi N, Katafuchi R, Tsuruya K, Nakano T, Kitazono T

Utility of Columbia classification in focal segmental glomerulosclerosis: renal prognosis and treatment response among the pathological variants.

Nephrol Dial Transplant 35(7): 1219-1227

Mihara A, Ohara T, Hata J, Honda T, Chen S, Sakata S, Oishi E, Hirakawa Y, Nakao T, Kitazono T, Ninomiya T

Association between serum glycated albumin and risk of cardiovascular disease in a Japanese community: the Hisayama Study.

Atherosclerosis 311: 52-59

Hirakawa Y, Hata J, Yoshinari M, Higashioka M, Yoshida D, Shibata M, Honda T, Sakata S, Kato H, Teramoto T, Maki H, Nishimoto S, Kitazono T, Ninomiya T

30-minute postload plasma glucose levels during an oral glucose tolerance test predict the risk of future type 2 diabetes: the Hisayama Study.

BMJ Open Diabetes Res Care 8(1): e001156

Yamasaki K, Hata J, Furuta Y, Hirabayashi N, Ohara T, Yoshida D, Hirakawa Y, Nakano T, Kitazono T, Ninomiya T

Association of albuminuria with white matter hyperintensities volume on brain magnetic resonance imaging in elderly Japanese - the Hisayama Study.

Circ J 84(6): 935-942

Sakata S, Hata J, Honda T, Hirakawa Y, Oishi E, Shibata M, Yoshida D, Goto K, Kitazono T, Ninomiya T

Serum uric acid levels and cardiovascular mortality in a general Japanese population: the Hisayama Study.

Hypertens Res 43(6): 560-568

Nagata T, Hata J, Sakata S, Oishi E, Honda T, Furuta Y, Ohara T, Yoshida D, Hirakawa Y, Shibata M, Ide T, Kitazono T, Tsutsui H, Ninomiya T

Serum N-terminal pro-B-type natriuretic peptide as a predictor for future development of atrial fibrillation in a general population: the Hisayama Study.

Int J Cardiol 320: 90-96

Higashioka M, Sakata S, Honda T, Hata J, Yoshida D, Hirakawa Y, Shibata M, Goto K, Kitazono T, Osawa H, Ninomiya T

Small dense low-density lipoprotein cholesterol and the risk of coronary heart disease in a Japanese community.

J Atheroscler Thromb 27(7): 669-682

Higashioka M, Hirakawa Y, Kawamura R, Honda T, Hata J, Yoshida D, Takata Y, Kitazono T, Osawa H, Ninomiya T

Ratios of serum eicosapentaenoic acid to arachidonic acid and docosahexaenoic acid to arachidonic acid were inversely associated with serum resistin levels: the Hisayama Study.

J Diabetes Investig 11(2): 482-489

Ohara T, Furuta Y, Hirabayashi N, Hata J, Hirakawa Y, Honda T, Yoshida D, Shibata M, Kitazono T, Ninomiya T

Elevated serum glycated albumin and glycated albumin : hemoglobin A_1c ratio were associated with hippocampal atrophy in a general elderly population of Japanese: the Hisayama Study.

J Diabetes Investig 11(4): 971-979

Hatabe Y, Shibata M, Ohara T, Oishi E, Yoshida D, Honda T, Hata J, Kanba S, Kitazono T, Ninomiya T

Decline in handgrip strength from midlife to late-life is associated with dementia in a Japanese community: the Hisayama Study.

J Epidemiol 30(1): 15-23

Chen S, Honda T, Ohara T, Hata J, Hirakawa Y, Yoshida D, Shibata M, Sakata S, Oishi E, Furuta Y, Kitazono T, Ninomiya T

Serum homocysteine and risk of dementia in Japan.

J Neurol Neurosurg Psychiatry 91(5): 540-546

Yoshida D, Ohara T, Hata J, Shibata M, Hirakawa Y, Honda T, Furuta Y, Oishi E, Sakata S, Kanba S, Kitazono T, Ninomiya T

Lifetime cumulative incidence of dementia in a community-dwelling elderly population in Japan.

Neurology 95(5): e508-e518

Hachiya T, Hata J, Hirakawa Y, Yoshida D, Furuta Y, Kitazono T, Shimizu A, Ninomiya T

Genome-wide polygenic score and the risk of ischemic stroke in a prospective cohort: the Hisayama Study.

Stroke 51(3): 759-765

Furue M, Ulzii D, Nakahara T, Tsuji G, Furue K, Hashimoto-Hachiya A, Kido- Nakahara M

Implications of IL-13Rα2 in atopic skin inflammation.

Allergol Int 69(3): 412-416

Tanaka Y, Ito T, Tsuji G, Furue M

Baicalein Inhibits Benzo[a]pyrene-Induced Toxic Response by Downregulating Src Phosphorylation and by Upregulating NRF2-HMOX1 System.

Antioxidants (Basel) 9(6): 507

Tsuji G, Hashimoto-Hachiya A, Yen VH, Takemura M, Yumine A, Furue K, Furue M, Nakahara T

Metformin inhibits IL-1β secretion via impairment of NLRP3 inflammasome in keratinocytes: implications for preventing the development of psoriasis.

Cell Death Discov 6: 11

Onozuka D, Nakamura Y, Tsuji G, Furue M

Mortality in Yusho patients exposed to polychlorinated biphenyls and polychlorinated dibenzofurans: a 50-year retrospective cohort study.

Environ Health 19(1): 119

Furue K, Ito T, Tanaka Y, Hashimoto-Hachiya A, Takemura M, Murata M, Kido- Nakahara M, Tsuji G, Nakahara T, Furue M

The EGFR-ERK/JNK-CCL20 Pathway in Scratched Keratinocytes May Underpin Koebnerization in Psoriasis Patients.

Int J Mol Sci 21(2): 434

Furue M, Furue K, Tsuji G, Nakahara T

Interleukin-17A and Keratinocytes in Psoriasis.

Int J Mol Sci 21(4): 1275

Vu YH, Hashimoto-Hachiya A, Takemura M, Yumine A, Mitamura Y, Nakahara T, Furue M, Tsuji G

IL-24 Negatively Regulates Keratinocyte Differentiation Induced by Tapinarof, an Aryl Hydrocarbon Receptor Modulator: Implication in the Treatment of Atopic Dermatitis.

Int J Mol Sci 21(24): 9412

Tsuji G, Hashimoto-Hachiya A, Yen VH, Miake S, Takemura M, Mitamura Y, Ito T, Murata M, Furue M, Nakahara T

Aryl Hydrocarbon Receptor Activation Downregulates IL-33 Expression in Keratinocytes via Ovo-Like 1.

J Clin Med 9(3): 891

Eto A, Nakahara T, Kido-Nakahara M, Tsuji G, Furue M

Acrosyringeal endothelin-1 expression: Potential for fostering melanocytes in volar sites.

J Dermatol 47(8): 924-925

Furue K, Ulzii D, Tanaka Y, Ito T, Tsuji G, Kido-Nakahara M, Nakahara T, Furue M

Pathogenic implication of epidermal scratch injury in psoriasis and atopic dermatitis.

J Dermatol 47(9): 979-988

Yumine A, Tsuji G, Furue M

Selective PPARα agonist pemafibrate inhibits TNF-α-induced S100A7 upregulation in keratinocytes.

J Dermatol Sci 99(1): 69-72

Furue K, Ito T, Tsuji G, Nakahara T, Furue M

Scratch wound-induced CXCL8 upregulation is EGFR-dependent in keratinocytes.

J Dermatol Sci 99(3): 209-212

Furue K, Ito T, Tsuji G, Nakahara T, Furue M

The CCL20 and CCR6 axis in psoriasis.

Scand J Immunol 91(3): e12846

Nakahara T, Kido-Nakahara M, Ulzii D, Miake S, Fujishima K, Sakai S, Chiba T, Tsuji G, Furue M

Topical application of endothelin receptor a antagonist attenuates imiquimod-induced psoriasiform skin inflammation.

Sci Rep 10(1): 9510

Ninomiya T, Nakaji S, Maeda T, Yamada M, Mimura M, Nakashima K, Mori T, Takebayashi M, Ohara T, Hata J, Kokubo Y, Uchida K, Taki Y, Kumagai S, Yonemoto K, Yoshida H, Muto K, Momozawa Y, Akiyama M, Kubo M, Ikeda M, Kanba S, Kiyohara Y; JPSFC-AD Study Group

Study design and baseline characteristics of a population-based prospective cohort study of dementia in Japan: the Japan Prospective Studies Collaboration for Aging and Dementia (JPSC-AD).

Environ Health Prev Med 25(1): 64

Tomiyama H, Vlachopoulos C, Xaplanteris P, Nakano H, Shiina K, Ishizu T, Kohro T, Higashi Y, Takase B, Suzuki T, Yamazaki T, Furumoto T, Kario K, Inoue T, Koba S, Takemoto Y, Hano T, Sata M, Ishibashi Y, Node K, Tanaka A, Maemura K, Ohya Y, Furukawa T, Ito H, Ohkuma T, Ninomiya T, Chikamori T, Yamashita A, Ueda S.

Usefulness of the SAGE score to predict elevated values of brachial-ankle pulse wave velocity in Japanese subjects with hypertension.

Hypertens Res 43(11): 1284-1292

Asayama K, Tabara Y, Oishi E, Sakata S, Hisamatsu T, Godai K, Kabayama M, Tatsumi Y, Hata J, Kikuya M, Kamide K, Miura K, Ninomiya T, Ohkubo T

Recent status of self-measured home blood pressure in the Japanese general population: a modern database on self-measured home blood pressure (MDAS).

Hypertens Res 43(12): 1403-1412

Imai Y, Hirata T, Saitoh S, Ninomiya T, Miyamoto Y, Ohnishi H, Murakami Y, Iso H, Tanaka S, Miura K, Tamakoshi A, Yamada M, Kiyama M, Ueshima H, Ishikawa S, Okamura T, Evidence for Cardiovascular Prevention from Observational Cohorts in Japan (EPOCH-JAPAN

Impact of hypertension stratified by diabetes on the lifetime risk of cardiovascular disease mortality in Japan: a pooled analysis of data from the Evidence for Cardiovascular Prevention from Observational Cohorts in Japan study.

Hypertens Res 43(12): 1437-1444

NCD Risk Factor Collaboration (NCD-RisC)(Ninomiya T, Hata J)

National trends in total cholesterol obscure heterogeneous changes in HDL and non-HDL cholesterol and total-to-HDL cholesterol ratio: a pooled analysis of 458 population-based studies in Asian and Western countries.

Int J Epidemiol 49(1): 173-192

Tully PJ, Yano Y, Launer LJ, Kario K, Nagai M, Mooijaart SP, Claassen JAHR, Lattanzi S, Vincent AD, Tzourio C; Variability in Blood Pressure and Brain Health Consortium; Variability in Blood Pressure and Brain Health Consortium (Ninomiya T, Ohara T, Oishi E)

Association between blood pressure variability and cerebral small-vessel disease: a systematic review and meta-analysis.

J Am Heart Assoc 9(1): e013841

McGrath ER, Himali JJ, Levy D, Conner SC, DeCarli C, Pase MP, Ninomiya T, Ohara T, Courchesne P, Satizabal CL, Vasan RS, Beiser AS, Seshadri S

Growth differentiation factor 15 and NT-proBNP as blood-based markers of vascular brain injury and dementia.

J Am Heart Assoc 9(19): e014659

Inaishi J, Saisho Y, Hirakawa Y, Yoshida D, Hata J, Mukai N, Watanabe Y, Oda Y, Itoh H, Ninomiya T

Association of glucose tolerance status with pancreatic β- and α-cell mass in community-based autopsy samples of Japanese individuals: the Hisayama Study.

J Diabetes Investig 11(5): 1197-1206

Yang Y, Hozawa A, Kogure M, Narita A, Hirata T, Nakamura T, Tsuchiya N, Nakaya N, Ninomiya T, Okuda N, Kadota A, Ohkubo T, Okamura T, Ueshima H, Okayama A, Miura K

Dietary inflammatory index positively associated with high-sensitivity C-reactive protein level in Japanese from NIPPON DATA2010.

J Epidemiol 30(2): 98-107

Ueda E, Yasuda M, Fujiwara K, Hashimoto S, Ohno-Matsui K, Hata J, Ishibashi T, Ninomiya T, Sonoda KH

Five-year incidence of myopic maculopathy in a general Japanese population: the Hisayama Study.

JAMA Ophthalmol 138(8): 887-893

Sasaki T, Tsuboi N, Marumoto H, Okabayashi Y, Haruhara K, Kanzaki G, Koike K, Ogura M, Ninomiya T, Yokoo T

Nephron number and time to remission in steroid-sensitive minimal change disease.

Kidney Med 2(5): 559-568.e1

NCD Risk Factor Collaboration (NCD-RisC)(Ninomiya T, Hata J)

Height and body-mass index trajectories of school-aged children and adolescents from 1985 to 2019 in 200 countries and territories: a pooled analysis of 2181 population-based studies with 65 million participants.

Lancet 396(10261): 1511-1524

Shibata M, Ninomiya T, Anno K, Kawata H, Iwaki R, Sawamoto R, Kubo C, Kiyohara Y, Sudo N, Hosoi M

Parenting style during childhood is associated with the development of chronic pain and a patient's need for psychosomatic treatment in adulthood: a case-control study.

Medicine (Baltimore) 99(29): e21230

NCD Risk Factor Collaboration (NCD-RisC)(Ninomiya T, Hata J)

Repositioning of the global epicentre of non-optimal cholesterol.

Nature 582(7810): 73-77

Ishida Y, Yoshida D, Honda T, Hirakawa Y, Shibata M, Sakata S, Furuta Y, Oishi E, Hata J, Kitazozno T, Ninomiya T

Influence of the accumulation of unhealthy eating habits on obesity in a general Japanese population: the Hisayama Study.

Nutrients 12(10): 3160

Lee CM, Woodward M, Batty GD, Beiser AS, Bell S, Berr C, Bjertness E, Chalmers J, Clarke R, Dartigues JF, Davis-Plourde K, Debette S, Di Angelantonio E, Feart C, Frikke-Schmidt R, Gregson J, Haan MN, Hassing LB, Hayden KM, Hoevenaar-Blom MP, Kaprio J, Kivimaki M, Lappas G, Larson EB, LeBlanc ES, Lee A, Lui LY, Moll van Charante EP, Ninomiya T, Nordestgaard LT, Ohara T, Ohkuma T, Palviainen T, Peres K, Peters R, Qizilbash N, Richard E, Rosengren A, Seshadri S, Shipley M, Singh-Manoux A, Strand BH, van Gool WA, Vuoksimaa E, Yaffe K, Huxley RR

Association of anthropometry and weight change with risk of dementia and its major subtypes: a meta-analysis consisting 2.8 million adults with 57 294 cases of dementia.

Obes Rev 21(4): e12989

Oku S, Takeshita T, Futatsuki T, Kageyama S, Asakawa M, Mori Y, Miyamoto T, Hata J, Ninomiya T, Kashiwazaki H, Yamashita Y

Disrupted tongue microbiota and detection of nonindigenous bacteria on the day of allogeneic hematopoietic stem cell transplantation.

PLoS Pathog 16(3): e1008348

Nobori T, Kawamura M, Yoshida R, Joichi T, Kamino K, Kishimura A, Baba E, Mori T, Katayama Y

Fluorescence Signal Amplification by Using β-Galactosidase for Flow Cytometry; Advantages of an Endogenous Activity-free Enzyme.

Anal Chem 92(4): 3069-3076

Yoshino T, Pentheroudakis G, Mishima S, Overman MJ, Yeh KH, Baba E, Naito Y, Calvo F, Saxena A, Chen LT, Takeda M, Cervantes A, Taniguchi H, Yoshida K, Kodera Y, Kitagawa Y, Tabernero J, Burris H, Douillard JY

JSCO/ESMO/ASCO/JSMO/TOS: International expert consensus recommendations for tumour-agnostic treatments in patients with solid tumours with microsatellite instability or NTRK fusions.

Ann Oncol 31(7): 861-872

Tsuruta N, Tsuchihashi K, Ohmura H, Yamaguchi K, Ito M, Ariyama H, Kusaba H, Akashi K, Baba B

RNA N6-methyladenosine demethylase FTO regulates PD-L1 expression in colon cancer cells.

Biochem Biophys Res Commun 530(1): 235-9

Jinnouchi F, Yamauchi T, Yurino A, Nunomura T, Nakano M, Iwamoto C, Obara T, Miyawaki K, Kikushige Y, Kato K, Maeda T, Miyamoto T, Baba E, Akashi K, Takenaka K

Establishment of a human SIRPA knock-in xenograft mouse model to study human hematopoietic and cancer stem cells.

Blood 135(19): 1661-1672

Ohmura H, Yamaguchi K, Hanamura F, Ito M, Makiyama A, Uchino K, Shimokawa H, Tamura S, Esaki T, Mitsugi K, Shibata Y, Oda H, Tsuchihashi K, Ariyama H, Kusaba H, Oda Y, Akashi K, Baba E

OX40 and LAG3 are associated with better prognosis in advanced gastric cancer patients treated with anti-programmed death-1 antibody.

Br J Cancer 122(10): 1507-1517

Sakai D, Taniguchi H, Sugimoto N, Tamura T, Nishina T, Hara H, Esaki T, Denda T, Sakamoto T, Okuda H, Satoh T, Tsushima T, Makiyama A, Tsuda T, Hosokawa A, Kuramochi H, Tokunaga S, Moriwaki T, Yasui H, Ishida H, Tsuji A, Otsu S, Shimokawa H, Baba E, Sato M, Matsumoto S, Ozaki Y, Shinozaki K, Tamagawa H, Goto M, Kadowaki S, Fujii H, Koh Y, Yamazaki K, Hironaka S, Kishimoto J, Boku N, Hyodo I, Muro K

Randomized phase II study of panitumumab plus irinotecan versus cetuximab plus irinotecan in patients with KRAS wild-type metastatic colorectal cancer refractory to fluoropyrimidine, irinotecan, and oxaliplatin (WJOG 6510G).

Eur J Cancer 135: 11-21

Ohmura H, Ito M, Uchino K, Okada C, Tanishima S, Yamada Y, Momosaki S, Komoda M, Kuwayama M, Yamaguchi K, Okumura Y, Nakano M, Tsuchihashi K, Isobe T, Ariyama H, Kusaba H, Oda Y, Akashi K, Baba E

Methylation of drug resistance-related genes in chemotherapy-sensitive Epstein-Barr virus-associated gastric cancer.

FEBS Open Bio 10(1): 147-157

Mishima S, Taniguchi H, Akagi K, Baba E, Fujiwara Y, Hirasawa A, Ikeda M, Maeda O, Muro K, Nishihara H, Nishiyama H, Takano T, Tsuchihara K, Yatabe Y, Kodera Y, Yoshino T

Japan Society of Clinical Oncology provisional clinical opinion for the diagnosis and use of immunotherapy in patients with deficient DNA mismatch repair tumors, cooperated by Japanese Society of Medical Oncology, First Edition

Int J Clin Oncol 25(2): 217-239

NaitoY, Aburatani H, Amano T, Baba E, Furukawa T, Hayashida T, Hiyama E, Ikeda S, Kanai M, Kato M, Kinoshita I, Kiyota N, Kohno T, Kohsaka S, Komine K, Matsumura I, Miura Y, Nakamura Y, Natsume A, Nishio K, Oda K, Oda N, Okita N, Oseto K, Sunami K, Takahashi H, Takeda M, Tashiro S, Toyooka S, Ueno H, Yachida S, Yoshino T, Tsuchihara K, Japanese Society of Medical Oncology; Japan Society of Clinical Oncology; Japanese Cancer Association

Clinical practice guidance for next‐generation sequencing in cancer diagnosis and treatment (edition 2.1).

Int J Clin Oncol 26(2): 233-283

Nio K, Tsuchihashi K, Taguchi K, Yoshihiro T, Yamaguchi K, Ito M, Moriyama S, Fukata M, Fujiwara T, Setsu N, Endo M, Matsumoto Y, Wakasaki T, Yasumatsu R, Ariyama H, Kusaba H, Kishimoto J, Akashi K, Baba E

Exploratory retrospective study of risk factors for thromboembolism treated with multi-kinase inhibitor pazopanib or lenvatinib.

Int J Surg Oncol 5(4): e89

Yamaguchi K, Ito M, Ohmura H, Hanamura F, Nakano M, Tsuchihashi K, Nagai S, Ariyama H, Kusaba H, Yamamoto H, Oda Y, Nakamura M, Akashi K, Baba E

Helper T cell-dominant tertiary lymphoid structures are associated with disease relapse of advanced colorectal cancer.

Oncoimmunology 9(1): 1724763

Tsuchihashi K, Kusaba H, Yoshihiro T, Fujiwara T, Setsu N, Endo M, Matsumoto Y, Imajima T, Shinohara Y, Ito M, Yamaga S, Tanoue K, Arimizu K, Ohmura H, Hanamura F, Yamaguchi K, Isobe T, Ariyama H, Nakashima Y, Akashi K, Baba E

Eribulin as a first-line treatment for soft tissue sarcoma patients with contraindications for doxorubicin.

Sci Rep 10(1): 20896

Kaku H, Funakoshi K, Ide T, Fujino T, Matsushima S, Ohtani K, Higo T, Nakai M, Sumita Y, Nishimura K, Miyamoto Y, Anzai T, Tsutsui H

Impact of Hospital practice factors on mortality in patients hospitalized for heasrt failure in Japan-An analysis of a large number of health records from a nationwide claims-based database, The JROAD-DPC.

Cric J 84(5): 742-753

Enzan N, Matsushima S, Ide T, Kaku H, Higo T, Tsuchihashi-Makaya M, Tsutsui H

Spironolactone use is associated with improved outcomes in heart failure with mid-range ejection fraction.

ESC Heart Fail 7(1): 339-347